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Related terms
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    Related terms
    • Brand Names: Canada: Apo-Floctafenine®

    • It is used to ease pain and swelling.
    • Floctafenine blocks chemicals that cause pain and swelling.


    How to take

    • Take with food to stop an upset stomach.
    • Take with a full glass of water.

    Missed Dose

    • Take a missed dose as soon as you think about it.
    • If it is close to the time for your next dose, skip the missed dose and go back to your normal time.
    • Do not take 2 doses at the same time or extra doses.
    • Many times this drug is taken on an as needed basis.


    • Store at room temperature.
    • Protect from light.
    • Protect from water. Do not store in a bathroom or kitchen.



    • Sometimes drugs are not safe when you take them with certain other drugs. Taking them together can cause bad side effects. This is one of those drugs. Be sure to talk to your doctor about all the drugs you take.


    • If you have an allergy to floctafenine or any other part of this drug.
    • This drug is not helpful during a migraine attack.
    • Tell your doctor if you are allergic to any drugs. Make sure to tell about the allergy and what signs you had. This includes telling about rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other signs.
    • If you have any of these health problems: Asthma, GI (gastrointestinal) disease, heart disease, liver disease, very bad kidney disease, ulcer or bleeding from stomach or bowel, or weak heart.
    • If you are more than 24 weeks pregnant.


    • If you have high blood pressure, talk with your doctor.
    • If you have kidney disease, talk with your doctor.
    • If you have had an ulcer or bleeding from your stomach or bowel, talk with your doctor.
    • Check all drugs you are taking with your doctor. This drug may not mix well with some other drugs.
    • Keep a list of all your drugs (prescription, natural products, vitamins, OTC) with you. Give this list to your doctor.
    • Talk with your doctor before using products that have aspirin, blood thinners, garlic, ginseng, ginkgo, ibuprofen or like products, pain drugs, or vitamin E.
    • Tell dentists, surgeons, and other doctors that you use this drug.
    • You may bleed more easily. Be careful and avoid injury. Use a soft toothbrush and an electric razor.
    • Do not take colestipol or cholestyramine within 2 hours of this drug.
    • Avoid beer, wine, or mixed drinks.
    • Tell your doctor if you are pregnant or plan on getting pregnant.
    • Tell your doctor if you are breast-feeding.

    Side Effects

    • Headache.
    • Belly pain.
    • Upset stomach or throwing up. Many small meals, good mouth care, sucking hard, sugar-free candy, or chewing sugar-free gum may help.
    • Loose stools (diarrhea).

    Contact a healthcare provider

    • If you think there was an overdose, call your local poison control center or ER right away.
    • Signs of a very bad reaction to the drug. These include wheezing; chest tightness; fever; itching; bad cough; blue or gray skin color; seizures; or swelling of face, lips, tongue, or throat.
    • Chest pain or pressure.
    • Change in strength on 1 side is greater than the other, trouble speaking or thinking, change in balance, or blurred eyesight.
    • Very upset stomach or throwing up.
    • Very bad belly pain.
    • Very bad swelling or pain of hands or feet.
    • A big weight gain.
    • Black, tarry, or bloody stools.
    • Blood in the urine.
    • Very loose stools (diarrhea).
    • Any bruising or bleeding.
    • Any rash.
    • Side effect or health problem is not better or you are feeling worse.

    General Statements

    • If you have a very bad allergy, wear an allergy ID at all times.
    • Do not share your drugs with others and do not take anyone else's drugs.
    • Keep all drugs out of the reach of children and pets.
    • Most drugs may be thrown away in household trash after mixing with coffee grounds or kitty litter and sealing in a plastic bag.
    • In Canada, take any unused drugs to the pharmacy. Also, visit to learn about the right way to get rid of unused drugs.
    • Keep a list of all your drugs (prescription, natural products, vitamins, OTC) with you. Give this list to your doctor.
    • Call your doctor for help with any side effects. If in the U.S., you may also call the FDA at 1-800-FDA-1088 or if in Canada, you may also call Health Canada's Vigilance Program at 1-866-234-2345.
    • Talk with the doctor before starting any new drug, including OTC, natural products, or vitamins.

    Author information
    • Copyright © 1978-2013 Lexi-Comp Inc. All rights reserved.

    Copyright © 2011 Natural Standard (

    The information in this monograph is intended for informational purposes only, and is meant to help users better understand health concerns. Information is based on review of scientific research data, historical practice patterns, and clinical experience. This information should not be interpreted as specific medical advice. Users should consult with a qualified healthcare provider for specific questions regarding therapies, diagnosis and/or health conditions, prior to making therapeutic decisions.

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